Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients
Table 1
Clinical and anthropometric characteristics of the study groups.
Characteristic
Control
Diabetes
1020
627
Age (years)
42.1 ± 7.3
53.2 ± 9.4
<0.001
Males, (%)
474 (46)
302 (48)
0.759
BMI (kg⋅m−2)
28.7 ± 4.9
29.7 ± 6.9
0.0016
Obesity, (%)
350 (34)
289 (46)
<0.001
Glucose (mg⋅dL−1)
95.5 ± 9.6
154 ± 73
<0.001
HbA1c
4.45 ± 0.8
7.27 ± 2.1
<0.001
Triglycerides (mg⋅dL−1)
183 ± 122
214 ± 140
<0.001
Total cholesterol (mg⋅dL−1)
201 ± 43
198 ± 52
0.2257
HDL-C (mg⋅dL−1)
49.5 ± 12.5
45.4 ± 13
<0.001
LDL-C (mg⋅dL−1)
129.2 ± 36
152.5 ± 56
<0.001
Creatinine (mg⋅dL−1)
1.17 ± 0.22
1.2 ± 0.92
0.4225
SBP
116 ± 14
121 ± 16
<0.001
DBP
77 ± 10
77.4 ± 10.6
0.102
Smoking, (%)
256 (25)
159 (25.3)
0.918
Continuous variables are presented as means ± SD and categorical variables as numbers (percentage). BMI, body mass index; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP: diastolic blood pressure.
