Research Article

Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats

Table 2

Measurements of parameters for determining efficacy of ExT.

ParametersWKY-SedWKY-ExTSHR-SedSHR-ExT

Body weight (BW, g)15320 ± 5292 ± 4305 ± 5280 ± 4
SMW (mg)15110 ± 3136 ± 4105 ± 5137 ± 4
SMW/BW (mg/g)150.34 ± 0.010.47 ± 0.010.34 ± 0.010.49 ± 0.01
CS in SMW (pg/mg)15672 ± 25790 ± 35685 ± 25778 ± 30
MAP (mmHg)10122 ± 3116 ± 6175 ± 5150 ± 5
HR (beats/min)10397 ± 8352 ± 9453 ± 8392 ± 7
NE in 24 h urine (g)100.41 ± 0.030.39 ± 0.050.71 ± 0.050.55 ± 0.04

: number of animals; MAP: mean arterial pressure; SMW: soleus muscle wet weight; CS: citrate synthase; MAP: mean arterial pressure; NE: norepinephrine; WKY-Sed: Wistar-Kyoto-sedentary; SHR-Sed: spontaneously hypertensive rat-sedentary; WKY-ExT: Wistar-Kyoto-exercise training; SHR-ExT: spontaneously hypertensive rat-exercise training. Data are mean ± SE. Values for MAP and HR were obtained in anaesthetized rats. MAP was measured by catheterizing femoral artery. versus WKY-Sed. versus SHR-Sed.