Research Article

Antioxidant Activity and Cytotoxicity Effect of Cocoa Beans Subjected to Different Processing Conditions in Human Lung Carcinoma Cells

Table 1

Effect of extracts of cocoa, cocoa nibs roasted slates (RS), and unroasted well fermented (UWF) cocoa (5–10 mg/mL) on cell cycle progression in human lung cancer cell line after 48 hours.

Cell cycle phaseCT5 mg/mL10 mg/mL

RSsub-G16.65 ± 1.0055.65 ± 0.4977.10 ± 2.26
75.75 ± 4.4530.65 ± 0.9220.63 ± 0.90
S5.40 ± 0.774.89 ± 0.160.74 ± 0.40
/M7.68 ± 1.776.73 ± 0.380.70 ± 0.64

UWFsub-G11.37 ± 0.2913.55 ± 2.6250.28 ± 7.09
75.80 ± 6.0225.65 ± 7.5721.78 ± 5.35
S5.61 ± 1.172.64 ± 1.582.20 ± 1.01
/M11.58 ± 3.5433.95 ± 3.0416.08 ± 4.01

Results are expressed as the percentage of total cells. The data represent mean ± SD values of triplicate experiments. Tukey's test; ; .