The Responses of Tissues from the Brain, Heart, Kidney, and Liver to Resuscitation following Prolonged Cardiac Arrest by Examining Mitochondrial Respiration in Rats

Table 1

Mitochondrial isolation yield (mg/g tissue) and respiration activities (NO/min/mg mitochondrial protein).

	Isolation yield				State-3
	Con.	CA30	CA45	CA30 + BP60	Con.	CA30	CA45	CA30 + BP60
Brain	1.52 ± 0.22	1.44 ± 0.33	1.61 ± 0.40	0.99 ± 0.41	150 ± 16.6	87.9 ± 20.9	71.2 ± 10.2	87.6 ± 37.3
Heart	20.4 ± 1.1	19.2 ± 2.3	19.9 ± 2.0	18.9 ± 2.4	178.3 ± 18.9	152.0 ± 28.1	124.0 ± 27.2	146.4 ± 16.6
Kidney	17.8 ± 2.8	14.6 ± 1.3	15.3 ± 1.0	15.1 ± 1.9	147.7 ± 8.7	82.4 ± 14.8	54.7 ± 15.5	103.3 ± 7.8
Liver	22.7 ± 2.4	16.3 ± 1.8	19.2 ± 2.2	26.6 ± 3.4	87.9 ± 11.7	65.1 ± 4.9	50.4 ± 6.9	89.8 ± 7.6
	State-4				Uncoupled
	Con.	CA30	CA45	CA30 + BP60	Con.	CA30	CA45	CA30 + BP60
Brain	21.4 ± 5.5	19.6 ± 6.0	20.9 ± 3.4	18.7 ± 4.6	166.3 ± 24.5	93.0 ± 29.2	74.6 ± 11.4	101.4 ± 54.8
Heart	21.4 ± 5.2	23.7 ± 6.0	35.8 ± 8.3	19.7 ± 4.1	182.8 ± 32.7	171.7 ± 21.6	140.0 ± 37.2	144.0 ± 17.4
Kidney	20.6 ± 2.8	16.3 ± 4.6	18.7 ± 5.0	15.4 ± 2.7	162.3 ± 10.3	91.1 ± 24.5	56.7 ± 20.7	115.0 ± 15.5
Liver	12.0 ± 3.1	11.9 ± 3.8	14.5 ± 2.4	12.5 ± 3.8	120.3 ± 22.2	97.9 ± 8.6	78.0 ± 12.0	127.1 ± 9.3

Against control; against CA30.