Research Article
Oxidative Stress Biomarkers and Left Ventricular Hypertrophy in Children with Chronic Kidney Disease
Table 3
Investigated clinical, biochemical, and echocardiographic parameters in the groups with oxLDL quartiles.
| | Parameter | oxLDL (U/L) | value | 41.4–67.4
() | 67.5–84.8
() | 86.0–103.5
() | 103.6–176.1
() |
| | SBP 24 h (-score) | 0.11
(−2.64; 0.53) | −0.62
(−0.92; 0.56) | −0.33
(−1.41; 1.30) | 1.86
(1.03; 2.73) | 0.009 |
| | DBP 24 h (-score) | −0.06
(−1.80; 0.27) | −0.77
(−2.14; 1.37) | −0.46
(−1.40; 1.78) | 2.42
(1.16; 4.64) | 0.004 |
| | MAP 24 h (-score) | 0.42
(−1.82; 0.79) | −0.32
(−1.09; 1.04) | 0.00
(−0.86; 1.76) | 2.32
(2.01; 4.45) | 0.003 |
| | Total chol. (mmol/L) | 4.19
(3.63; 4.81) | 4.48
(4.13; 5.01) | 4.67
(4.08; 5.62) | 6.19
(5.39; 7.50) | 0.001 |
| | TGL (mmol/L) | 1.21
(0.90; 1.62) | 1.30
(1.08; 1.47) | 1.69
(1.28;2.35) | 2.62
(1.63; 3.70) | 0.001 |
| | HDL (mmol/L) | 1.35
(1.08; 1.76) | 1.35
(1.17; 1.76) | 1.19
(1.03;1.43) | 1.26
(0.97; 1.62) | 0.417 |
| | LDL (mmol/L) | 2.07
(1.70; 2.59) | 2.43
(1.99; 2.64) | 2.49
(2.08; 3.39) | 3.26
(2.57; 4.01) | 0.005 |
| | Cystatin (mg/L) | 1.36
(1.09; 2.97) | 2.36
(1.17; 3.46) | 2.55
(1.61; 4.07) | 4.24
(1.48; 6.12) | 0.053 |
| | Albumin (g/L) | 46.0
(44.1; 48.0) | 46.0
(44.0; 47.7) | 45.0
(38.3; 47.0) | 43.0
(34.0; 47.6) | 0.320 |
| | hsCRP (ng/mL) | 267.5
(159.5; 688.2) | 321.9
(162.5; 553.4) | 459.2
(104.3; 1270.2) | 273.2
(121.5; 486.4) | 0.939 |
| | ICAM-1 (ng/mL) | 295.5
(267.3; 339.4) | 303.0
(288.5; 346.4) | 339.9
(316.0; 405.8) | 326.4 (278.4; 396.7) | 0.373 |
| | Carbonyl groups (nmol/mg) | 1.39
(0.87; 1.69) | 1.73
(0.50; 2.25) | 1.23
(0.96; 1.87) | 0.92
(−0.54; 1.75) | 0.736 |
| | LVM (-score) | 0.05
(−1.06; 0.76) | −0.27
(−0.99; 0.64) | 0.73
(−0.41; 1.70) | 1.01
(−0.05; 2.61) | 0.038 |
| | LVEDd -score | 0.17
(−0.61; 0.85) | 0.19
(−0.19; 0.61) | −0.03
(−0.60; 0.57) | 0.22
(−0.31; 0.83) | 0.765 |
| | IVSd -score | 0.99
(.07; 1.42) | 0.31
(−0.06; 0.93) | 1.06
(0.18; 1.72) | 1.08
(0.56; 2.07) | 0.082 |
| | LVPWT -score | 0.75
(0.18; 1.40) | 1.32
(0.26; 1.58) | 1.40
(0.50; 2.19) | 1.45
(0.65; 2.37) | 0.281 |
|
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Values presented as median (25th–75th percentile).
SBP 24 h—systolic blood pressure 24 h; DBP 24 h—diastolic blood pressure 24 h; MAP 24 h—mean arterial pressure 24 h; TGL—triglycerides; HDL—high-density lipoprotein; LDL—low-density lipoprotein; hsCRP—high sensitive C-reactive protein; oxLDL—oxidized low-density lipoprotein; ICAM-1—intercellular adhesion molecule-1; LVM—left ventricular mass; LVEDd—left ventricular end-diastolic dimension; IVSd—interventricular septum at end diastole; LVPWd— left ventricular posterior wall thickness at end diastole.
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