Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondrial Dysfunction in Rat Liver Mitochondria and Hepatocytes

Figure 2

Respiration with glutamate and malate after exposure to EGCG and/or tBHP. (a) Leak respiration in isolated mitochondria; (b) leak respiration in permeabilized hepatocytes; (c) ADP-stimulated respiration in isolated mitochondria; (d) ADP-stimulated respiration in permeabilized hepatocytes. The concentrations of EGCG are expressed in μmol/L, and those of tBHP are in mmol/L. versus control, + versus corresponding EGCG alone, # versus tBHP alone; , <0.01, or <0.001 for one, two or three symbols, respectively; –10.

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