Cathepsin B Regulates Collagen Expression by Fibroblasts via Prolonging TLR2/NF-κB Activation

Figure 4

The immunofluorescent CLSM images of TLR2, CatB, and 8-OHdG (green) with fibronectin (red) and Hoechst-stained nuclei (blue) in the inflamed tissues of patients with chronic periodontitis. Scale bar = 50 μm. The magnifical images are made from the square areas. The increased CatB is closely related to the oxidative damage during the chronic activation of TLR2/NF-κB signaling.