Endogenous n-3 Fatty Acids Alleviate Carbon-Tetrachloride-Induced Acute Liver Injury in Fat-1 Transgenic Mice

Table 3

Fatty acid composition (%) of liver tissues.

Fatty acids			% of total fatty acids
Common name	Symbol		WT	WT/CCl4	Fat-1/CCl4
Lauric acid	12:0		0.27 ± 0.22	0.23 ± 0.15	0.26 ± 0.22
Myristic acid	14:0		0.84 ± 0.28	0.60 ±	0.76 ±
Palmitic acid	16:0		28.5 ± 4.3	24.4 ±	26.7 ± 3.8
Palmitoleic acid	16:1		1.16 ± 0.43	1.59 ±	1.32 ±
Stearic acid	18:0		23.0 ± 7.4	14.5 ±	19.5 ±
Oleic acid	18:1		15.1 ± 5.0	20.8 ±	17.7 ±
Linolenic acid	18:2,6		17.1 ± 5.6	24.6 ±	21.3 ±
γ-Linolenic acid	18:3,6		0.41 ± 0.20	0.35 ± 0.10	0.28 ± 0.16
α-Linolenic acid	18:3,3		0.27 ± 0.05	0.22 ± 0.05	0.36 ±
Arachidic acid	20:0		0.45 ± 0.18	0.23 ±	0.41 ±
Eicosenoic acid	20:1		0.26 ± 0.06	0.26 ± 0.03	0.25 ± 0.05
Dihomo-γ-linoleic acid	20:3,6		0.43 ± 0.14	0.60 ±	0.43 ±
Arachidonic acid	20:4,6		9.08 ± 1.48	8.21 ± 1.86	4.73 ±
Eicosapentaenoic acid	20:5,3		0.03 ± 0.02	0.04 ± 0.03	0.42 ±
Behenic acid	22:0		0.17 ± 0.05	0.15 ± 0.05	0.17 ± 0.01
Erucic acid	22:1		0.20 ± 0.06	0.18 ± 0.11	0.29 ±
Docosadienoic acid	22:2,6		0.25 ± 0.10	0.10 ±	0.02 ±
Docosatetraenoic acid	22:4,6		0.28 ± 0.16	0.45 ±	0.22 ±
Docosapentaenoic acid	22:5,3		0.04 ± 0.03	0.07 ± 0.06	0.15 ± 0.21
Lignoceric acid	24:0		0.02 ± 0.01	0.02 ± 0.02	0.01 ± 0.01
Docosahexaenoic acid	22:6,3		1.67 ± 0.39	1.94 ± 0.33	4.16 ±
Nervonic acid	24:1		0.09 ± 0.04	0.20 ±	0.13 ± 0.09
SFAs			53.5 ± 11.9	40.4 ±	48.1 ±
MUFAs			16.9 ± 5.5	23.1 ±	19.8 ±
n-3 PUFAs			2.04 ± 0.38	2.30 ± 0.33	5.1 ±
n-6 PUFAs			27.5 ± 6.5	34.3 ± 2.8	27.0 ±
Total PUFAs			29.6 ± 6.8	36.6 ± 3.0	32.2 ± 6.8
n-6/n-3 PUFAs			13.4 ± 1.5	15.1 ± 1.7	5.40 ±
16:1/16:0			0.04 ± 0.02	0.07 ±	0.05 ± 0.02
18:1/18:0			0.80 ± 0.52	1.51 ±	1.01 ±

Values are expressed as the means ± SD (); and versus WT group; and versus WT/CCl₄ group. SFA: saturated fatty acid; MUFA: monounsaturated fatty acid; PUFA: polyunsaturated fatty acid.