Oral Exposure to Atrazine Induces Oxidative Stress and Calcium Homeostasis Disruption in Spleen of Mice

Figure 7

Effects of ATR on expression of NF-κB and Ref-1 proteins in spleens. Mice were exposed by daily oral gavage to ATR doses for 21 days. Tissues were harvested 24 hr after the final dosing. Semiquantitative Western blotting was used to analyze expression of NF-κB and Ref-1. Representative blots for NF-κB and Ref-1 and respective blot for -actin used for normalization are presented in (a). (b) Showing quantification results expressed as fold-change of the ratio of target protein/-actin in each group. Data shown are means SE of three independent experiments. Asterisks illustrate statistically significant difference versus control ().

(a)

(b)