Research Article
Cardioprotective Effects of Astragalin against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart
Table 2
Effect of astragalin on levels of LDH and CK in coronary flow (values are presented as mean
SD,
).
| Physical index | Before ischemia | Reperfusion | 20 min | 20 min | 45 min |
| LDH (U/L) | | | | Control | 10.65 ± 0.24 | 10.26 ± 0.15 | 10.13 ± 0.30 | I/R | 10.64 ± 0.14 | 26.81 ± 0.19 | 24.48 ± 0.30 | 5 μmol/L astragalin | 11.81 ± 0.05 | 20.41 ± 0.13 | 19.49 ± 0.16 | 10 μmol/L astragalin | 12.46 ± 0.33 | 12.56 ± 0.21 | 10.67 ± 0.17 | 20 μmol/L astragalin | 12.84 ± 0.42 | 17.94 ± 0.54 | 15.72 ± 0.25 | CK (U/L) | | | | Control | 29.03 ± 0.53 | 25.68 ± 0.50 | 26.18 ± 0.46 | I/R | 29.89 ± 2.74 | 352.06 ± 19.80 | 131.14 ± 8.32 | 5 μmol/L astragalin | 26.56 ± 2.55 | 265.95 ± 16.67 | 106.74 ± 13.02 | 10 μmol/L astragalin | 27.96 ± 1.97 | 237.31 ± 15.27 | 89.82 ± 12.15 | 20 μmol/L astragalin | 24.09 ± 2.39 | 248.64 ± 13.99 | 93.97 ± 16.08 |
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and compared with control group; and compared with the I/R group.
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