The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes

Figure 5

Effect of lycopene and UV-B on the cell cycle: (a) cell cycle histograms of UV-B (225 mJ/cm²) irradiated (IR) and nonirradiated (NI) HaCaT cells exposed to 10 μM complexed lycopene (Lyc-CD) and to the respective controls; (b) cell cycle phase distribution of UV-B (225 mJ/cm²) irradiated (IR) and nonirradiated (NI) HaCaT cells exposed to 10 μM complexed lycopene (Lyc-CD) and the respective controls, including cyclodextrin vehicle (NI, CD and IR, CD). Results are expressed as percentage (mean ± SD). Statistical analysis: One-Way ANOVA with All Pairwise Multiple Comparison Procedures: means with different letters (A, B, and C) are significantly different (). In this case, only the statistical differences between groups presenting differences (G0/G1 and sub-G1) were marked for simplification purposes. Comparison between % cells with sub-G1 amount of DNA (#) and % cells in G0/G1 phase () is presented.

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