Research Article

AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer’s Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Figure 5

AP39 protected mitochondrial function in APP/PS1 neurons. (a) AP39 increased the cellular ATP levels. (b) AP39 protected mtDNA integrity. (c) ROS levels were detected by flow cytometry. (d) AP39 reduced ROS levels. , compared with the WT group; , compared with the control group (H2O).