Experimental Colitis Is Attenuated by Cardioprotective Diet Supplementation That Reduces Oxidative Stress, Inflammation, and Mucosal Damage

Figure 3

Corabion prevents neutrophil recruitment and oxidative stress. (a) Measurement of myeloperoxidase (MPO) activity as means of leukocyte recruitment in the four experimental groups: control (ctrl), colitis, colitis and corabion, and control and corabion. per group; . (b) Fluorescence images of oxidized ethidium depicted in grayscales as means of ROS production and oxidative stress in colon tissues of the four experimental groups. Representative images of 3 independent tissue preparations are shown. Bar = 50 μm. (c) Ratio of reduced tetrahydrobiopterin (BH4) to oxidized dihydrobiopterin (BH2) in mouse serum as measure of systemic oxidative stress is shown. ; ; .

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