Experimental Colitis Is Attenuated by Cardioprotective Diet Supplementation That Reduces Oxidative Stress, Inflammation, and Mucosal Damage
Corabion prevents neutrophil recruitment and oxidative stress. (a) Measurement of myeloperoxidase (MPO) activity as means of leukocyte recruitment in the four experimental groups: control (ctrl), colitis, colitis and corabion, and control and corabion. per group; . (b) Fluorescence images of oxidized ethidium depicted in grayscales as means of ROS production and oxidative stress in colon tissues of the four experimental groups. Representative images of 3 independent tissue preparations are shown. Bar = 50 μm. (c) Ratio of reduced tetrahydrobiopterin (BH4) to oxidized dihydrobiopterin (BH2) in mouse serum as measure of systemic oxidative stress is shown. ; ; .