Interplay between Superoxide Dismutase, Glutathione Peroxidase, and Peroxisome Proliferator Activated Receptor Gamma Polymorphisms on the Risk of End-Stage Renal Disease among Han Chinese Patients
Table 3
Characteristics of patients with ESRD and those without CKD.
Variables
Non-CKD
ESRD patients
Number of subjects
780
671
Age (years)
60.0 ± 19.2
58.9 ± 14.6
<0.001
Male
410 (52.6%)
327 (48.7%)
0.155
DM
83 (10.6%)
253 (37.7%)
<0.001
Serum creatinine (mg/dL)
1.0 ± 0.3
11.2 ± 2.5
<0.001
SOD2 exon 2 genotype
0.036
TT
576 (73.85%)
455 (67.8%)
CT
190 (24.36%)
199 (29.66%)
CC
14 (1.79%)
17 (2.53%)
GPX1 exon 2 genotype
1.000
CC
697 (89.36%)
600 (89.42%)
CT
82 (10.51%)
71 (10.58%)
TT
1 (0.13%)
0 (0.00%)
PPAR- exon B genotype
0.028
CC
733 (93.90%)
609 (90.99%)
CG
46 (5.97%)
57 (8.30%)
GG
1 (0.13%)
5 (0.72%)
PPAR- exon 6 genotype
0.382
CC
449 (57.69%)
366 (55.08%)
CT
283 (36.21%)
254 (37.63%)
TT
48 (6.10%)
51 (7.30%)
Continuous variables were tested by Kruskal-Wallis test, whereas categorical variables were tested by Fisher’s exact test.
