Oxidative Medicine and Cellular Longevity

Research Article

Interplay between Superoxide Dismutase, Glutathione Peroxidase, and Peroxisome Proliferator Activated Receptor Gamma Polymorphisms on the Risk of End-Stage Renal Disease among Han Chinese Patients

Table 4

Characteristics of ESRD patients due to DMN and non-DMN related ESRD.
VariablesNon-DMN-related ESRD patientsDMN-related ESRD patients
Number of subjects492179 
SOD2 exon 2 genotype  0.716
 TT 330 (67.1%) 125 (69.8%) 
 CT 150 (30.5%) 49 (27.4%) 
 CC12 (2.4%)5 (2.8%) 
GPX1 exon 2 genotype  0.258
 CC 444 (90.2%) 156 (87.2%) 
 TC48 (9.8%) 23 (12.8%) 
 TT 0 (0.00%) 0 (0.00%) 
PPAR- exon B genotype  0.284
 CC 451 (91.7%) 158 (88.3%) 
 CG 37 (7.5%) 20 (11.2%) 
 GG 4 (0.8%) 1 (0.6%) 
PPAR- exon 6 genotype  0.454
 CC 263 (53.5%) 103 (57.5%) 
 CT 193 (39.2%) 61 (34.1%) 
 TT36 (7.3%) 51 (8.4%) 
Continuous variables were tested by Kruskal-Wallis test, whereas categorical variables were tested by Fisher’s exact test.