Beneficial Effects of Physical Exercise on Functional Capacity and Skeletal Muscle Oxidative Stress in Rats with Aortic Stenosis-Induced Heart Failure

Table 6

Echocardiographic evaluation of left ventricle diastolic function.

	C-Sed ()	C-Ex ()	AS-Sed ()	AS-Ex ()
Mitral E (cm/s)	79.5 (73.0–84.0)	81.5 (76.0–89.0)	142 (89.0–165)	145 (85.0–159)^†
Mitral A (cm/s)	59.5 (51.0–67.0)	60.0 (51.0–76.0)	24.0 (22.0–47.5)	22.5 (16.0–59.0)^†
E/A	1.40 (1.22–1.53)	1.34 (1.17–1.60)	5.85 (1.73–7.15)	7.50 (1.47–9.16)^†
IVRT (ms)	24.0 (22.0–26.0)	22.0 (21.2–26.0)	18.0 (15.0–22.0)	16.0 (15.0–22.0)^†
IVRTn	53.0 ± 7.25	51.2 ± 8.37	42.6 ± 11.4	39.0 ± 10.2^†
EDT (ms)	45.0 (41.0–52.0)	47.0 (41.0–53.0)	28.0 (23.0–35.0)	29.0 (24.5–33.0)^†
TDI E (average mm/s)	4.37 (3.95–4.95)	4.50 (4.35–4.92)	4.25 (3.04–4.90)	4.17 (3.50–5.25)
TDI A (average mm/s)	4.50 ± 1.37	4.37 ± 1.21	3.79 ± 1.47	4.12 ± 1.07
E/TDI E (average)	17.9 (15.8–20.0)	18.4 (15.7–20.2)	33.0 (25.7–41.3)	32.1 (24.8–40.6)^†

C-Sed: sedentary control group; C-Ex: exercised control group; AS-Sed: sedentary aortic stenosis group; AS-Ex: exercised aortic stenosis group. E/A: ratio between early- (E-) to-late (A) diastolic mitral inflow; IVRT: isovolumetric relaxation time; IVRTn: IVRT normalized to heart rate; EDT: E wave deceleration time; TDI E and A: tissue Doppler imaging (TDI) of early (E) and late (A) diastolic velocity of mitral annulus. ANOVA and Tukey or Mann-Whitney; versus C-Sed; ^† versus C-Ex.