Induction of Expression of p75 Neurotrophin Receptor Intracellular Domain Does Not Induce Expression or Enhance Activity of Mitochondrial Complex II

Figure 3

Complex II activity in NIH 3T3 cells transfected with expression constructs for p75ICD, p75ICD minus the chopper domain, or p75NTR death domain as described in [6] relative to activity in mock-transfected NIH 3T3 cells (set at 1.0). Complex II activity does not differ from that in mock-transfected cells for any of the p75ICD fragment transfectants (, Student’s -test). Error bars show SEM for three independent experiments, each with quadruplicate samples.