Lower Serum Caveolin-1 Is Associated with Cerebral Microbleeds in Patients with Acute Ischemic Stroke

Table 3

Logistic regression analysis for association between Cav-1 and CMBs subgroups.

Cav-1	CMBs location
	Deep or infratentorial CMBs ()				Strictly lobar CMBs ()
	Model 1		Model 2		Model 1		Model 2
≤5.25 ng/mL	3.54 (1.58–7.92)	0.002	4.04 (1.59–10.25)	0.003	1.85 (0.60–5.69)	0.286	1.55 (0.43–5.60)	0.501
>5.25 ng/mL	Reference		Reference		Reference		Reference
Cav-1	CMBs number
	Multiple CMBs ()				Single CMBs ()
	Model 1	P	Model 2	P	Model 1	P	Model 2	P
≤5.25 ng/mL	2.70 (1.18–6.17)	0.018	3.18 (1.16–8.72)	0.025	2.72 (0.99–7.45)	0.052	3.03 (0.95–9.72)	0.062
>5.25 ng/mL	Reference		Reference		Reference		Reference

Model 1, adjusted for age and sex; Model 2, adjusted for age, sex, hypertension, diabetes mellitus, dyslipidemia, heart disease, BMI, smoking, alcohol intake, SBP, DBP, antithrombotics use, onset-to-MRI time, onset-to-blood drawing time, NIHSS, fasting glucose, triglycerides, HDL, LDL, total cholesterol, and fibrinogen.
CMBs, cerebral microbleeds.