Maresin 1, a Proresolving Lipid Mediator, Mitigates Carbon Tetrachloride-Induced Liver Injury in Mice

Figure 1

MaR 1 treatment inhibited CCl4 induced liver injury in mice. Representative micrographs and necrosis area from control mice (control), vehicle plus CCl4 (0.1 mL/kg i.p.), and MaR 1 treated of hematoxylin-eosin staining of liver section (a and b). The change of serum alanine aminotransferase (ALT) level (c) and aspartate aminotransferase (AST) activities (d) in CCl4 treated mice. Original magnification ×200. Arrows indicate necrotic area. Data are expressed as means ± SEM. . versus the control group, versus the CCl4 treated group.

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