Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System

Figure 3

Temperature effects on antioxidant status in isolated perfused rat livers. IPR livers were perfused at 37°C for 15 min and then at the indicated temperatures for 15 min more. Bar graphs show hepatic GSH (a), GSH/GSSG ratio (b), and GSH-reductase activity (c). Values expressed as mean ± SEM of . Significant differences from livers perfused at 37°C: , , and . Significant differences from livers perfused at 26°C: and .

(a)

(b)

(c)