Research Article

Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients

Table 4

Results of oxidative stress markers determined in serum and total blood of the study participants.


Control Patients with ALC
ALCChild-Pugh AChild-Pugh BChild-Pugh C

Sex, F/M
(%)
39/91
(30/70)
2/55
(3.5/96.4)
1/21
(1.8/36.8)
1/25
(1.8/43.8)
0/9
(0/15.7)
Carbonylated proteins (nmol carbonylated prot./mg prot.)0.05 ± 0.0070.05 ± 0.0070.05 ± 0.010.04 ± 0.010.08 ± 0.01
MDA (nmol MDA/mg prot.)0.1 ± 0.010.2 ± 0.18 ± 0.2 ± 0.3 ±
GSH (M)530.6 ± 9.1475.5 ± 40.3191. 3 ± 683.1 ± 570.3 ±
GSSG (M)207.8 ± 16.6368.9 ± 663.3 ± 176.8 ± 204.6 ±
GSH/GSSG ratio2.1 ± 0.20.1 ± 1.5−0.5 ± 2.2−0.5 ± 2.83.8 ± 1.2

Values represented as the mean ± SEM. , control group versus ALC group; , control group versus Child-Pugh A subgroup; , control group versus Child-Pugh B patients; , control group versus Child-Pugh C subgroup; , Child-Pugh A versus Child-Pugh B subgroups; , Child-Pugh A subgroup versus Child-Pugh C patients; , Child-Pugh B patients versus Child-Pugh C subgroup.