Effects of Astragalus Polysaccharides on Dysfunction of Mitochondrial Dynamics Induced by Oxidative Stress

Table 2

Fusion and fission-related genes mRNA expression in vivo.

	SED	EXE	SED + APS	EXE + APS
Mfn-1	1.00	0.60 ± 0.05	1.09 ± 0.15	0.83 ± 0.28
Mfn-2	1.00	0.70 ± 0.15	1.05 ± 0.12	0.85 ± 0.03
Opa-1	1.00	0.90 ± 0.05	0.93 ± 0.15	1.04 ± 0.30
Drp-1	1.00	2.33 ± 0.28	1.10 ± 0.25	1.67 ± 0.13
Fis-1	1.00	1.04 ± 0.47	1.01 ± 0.26	1.14 ± 0.12

Mfn-1: mitofusin 1; Mfn-2: mitofusin 2; Opa-1: optic atrophy 1; Drp-1: dynamin-related protein q; Fis-1: mitochondrial fission 1 protein. Significant difference between EXE and SED groups (-test; ). Significant difference between EXE and EXE + APS groups (-test; ).