Research Article
Nr2e1 Deficiency Augments Palmitate-Induced Oxidative Stress in Beta Cells
Figure 1
Knockdown of Nr2e1 results in reduced expression of Nr2e1 in MIN6 cells. (a) mRNA expression of Nr2e1 in MIN6 cells transduced with shRNA lentivirus targeted against mouse Nr2e1 (MIN6-sh1, MIN6-sh2, and MIN6-sh3) or scrambled nontarget negative control (MIN6-shc). (b) Reduced protein expression of Nr2e1 MIN6-sh1, MIN6-sh2, and MIN6-sh3 cells. Results are means ± SD for three observations. . All comparisons with MIN6-shc cells.
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