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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 9734816, 9 pages
Review Article

Overview of the Role of Vanillin on Redox Status and Cancer Development

1Gonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ-BA), Salvador, BA, Brazil
2Department of Pharmaceutical Sciences, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB, Brazil

Received 17 September 2016; Revised 4 November 2016; Accepted 21 November 2016

Academic Editor: Kum Kum Khanna

Copyright © 2016 Daniel Pereira Bezerra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bioactive natural products play critical roles in modern drug development, especially anticancer agents. It has been widely reported that various pharmacological activities of such compounds are related to their antioxidant properties. Vanillin is a natural substance widely found in many plant species and often used in beverages, foods, cosmetics, and pharmaceutical products. Antioxidant and anticancer potential have been described for this compound. Considering the importance of vanillin in the area of human health and food and pharmaceuticals sectors, in this review, we discuss the role of vanillin on redox status and its potential contribution to the prevention and the treatment of cancer.