Oxidative Stress Markers and Their Dynamic Changes in Patients after Acute Ischemic Stroke

Table 2

Levels of oxidative stress markers and activities of antioxidant enzymes in experimental groups of ischemic stroke patients (A, B, C) and healthy controls.

Parameter (units)	Co	A	B	C
Lipid peroxides in plasma; (nmol/mL)	43.48 ± 2.98	55.09 ± 3.55	43.62 ± 3.72	44.37 ± 5.47
8-Isoprostanes in urine; (ng/mmol creatinin)	32.57 ± 4.40	68.69 ± 10.93	43.72 ± 8.65	43.89 ± 12.70
Protein carbonyls in plasma; (nmol/mg protein)	0.25 ± 0.04	0.22 ± 0.03	0.28 ± 0.04	0.20 ± 0.07
TEAC in plasma; (mmol/L)	1.49 ± 0.13	1.64 ± 0.12	1.47 ± 0.17	2.77 ± 0.17
PON1 in serum; (U/mL)	104.07 ± 3.04	86.45 ± 3.57	85.86 ± 4.61	102.39 ± 7.95
SOD in hemolysates; (U/mg Hb)	661.44 ± 7.15	697.62 ± 8.95	750.45 ± 9.72	747.41 ± 17.27
Catalase in hemolysates; (µkat/g Hb)	3.61 ± 0.17	4.92 ± 0.17	6.56 ± 0.24	4.85 ± 0.21
GPx in hemolysates; (U/g Hb)	24.83 ± 1.24	36.16 ± 4.91	26.28 ± 1.51	23.55 ± 2.60

Data are presented as means ± SEM. Co: control individuals; A: patients within 24 h after AIS, B: patients at 7-day follow-up, and C: patients at 3-month follow-up; TEAC: trolox equivalent antioxidant capacity of plasma; PON1: paraoxonase activity; SOD: superoxide dismutase activity; GPx: glutathione peroxidase activity; Hb: hemoglobin. < 0.05; < 0.01; < 0.001 versus controls.