Research Article

Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

Figure 1

Ebselen treatment prevented the increased levels of 3-NT-ir. (a) Representative effects of Ebselen on positive 3-NT immunoreactivity (3-NT-ir) in CBs from rats exposed to CIH. Inset, negative controls omitted inclusion of primary antibody. Scale bars 20 μm. (b) Summary of the effects of Ebselen on 3-NT-ir measured in CBs. , vehicle CIH versus Ebselen sham and Ebselen CIH, and Bonferroni after one-way ANOVA, rats per group.
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