Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

Figure 3

Ebselen reversed the increased arterial blood pressure measured during normoxia in CIH rats. Telemetric recording realized in the same rat during control condition ((a), sham), after 7 days of CIH ((a), CIH) and the effect of Ebselen after additional 7 days of CIH ((a), Ebselen CIH). Summary of the effect of Ebselen on mean arterial blood pressure (MABP, (b)) and heart rate (HR, (c)). , CIH versus sham and Ebselen CIH, and Newman-Keuls after Repeated Measures ANOVA, rats.

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(b)

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