Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Carbonyl compounds</td><td align="left">Carbonyl clearance</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Acrolein (CH2=CHCHO) Glyoxal (OHCCHO) Methylglyoxal (CH3COCHO) Crotonaldehyde (CH3CH=CHCHO) Malondialdehyde (OCHCH2CHO) 4-Hydroxynonenal (OCHCH=CHCH(-OH)(CH2)4CH3)</td><td align="left">(1) Glutathione-S-transferases (GST) catalyze carbonyl-glutathione conjugation (2) Aldehyde reductase and aldo-keto reductases (AKRs) catalyze reduction to alcoholic forms (3) Aldehyde dehydrogenases catalyze oxidation to carbonic acids</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Oxidative Medicine and Cellular Longevity

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Table 2

Table 2: Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer 