Mitochondrial Ferritin Deletion Exacerbates β-Amyloid-Induced Neurotoxicity in Mice

Figure 2

The effect of Ftmt ablation on A -induced neuronal cell apoptosis. Apoptotic cell death was assessed by DAPI and TUNEL staining, as described in the Materials and Methods section. (a) Representative photographs (original magnification 100x) of the dentate gyrus of the hippocampus of mouse brains. (b) The statistical analysis of relative apoptotic cell levels. Data are presented as the mean ± SD, . versus WT + saline group, versus KO + saline group, and versus WT + A group.

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