Antioxidant, Cytotoxic, and Toxic Activities of Propolis from Two Native Bees in Brazil: Scaptotrigona depilis and Melipona quadrifasciata anthidioides

Figure 5

Cytotoxic action of EEP from M. q. anthidioides against the K562 erythroleukemia cell line. (a) Representative diagrams obtained via flow cytometry of cells stained with annexin V-FITC/PI: the lower left quadrant (PI−/An−) represents viable cells; the lower right quadrant (PI−/An+) represents apoptotic cells; the upper left quadrant (PI+/An−) represents cells in necrosis; and the upper right quadrant (PI+/An+) represents cells in late apoptosis. (b) Frequency of cell death, obtained from the corresponding diagrams for the tested concentrations. for the treated group versus control viable cells. for the treated group versus control apoptosis. for the treated group versus control necrosis. for the treated group versus control late apoptosis.

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