Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats

Figure 3

Heart of (a) normal control rats and (b) normal rats treated with simvastatin showing normal histological appearance of both myocardial cell cytoplasm (arrow) and nuclei (arrow head), (c) STZ-induced diabetic rats showing many myocardial cells with degenerated cytoplasm (arrow) and pyknotic nuclei (arrow head), and (d) diabetic rats treated with simvastatin showing decreased degeneration of myocardial cell cytoplasm (arrows) and nuclei (arrow heads). (H&E).

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