Oxidative Stress-Related Parthanatos of Circulating Mononuclear Leukocytes in Heart Failure

Table 1

Clinical parameters and anamnestic data of study groups.

	Control	Chronic heart failure	Sign
Number	15	20
Gender: male/female	13/2	16/4	n.s.
Age (years)	63.3 ± 9.4	68.9 ± 8.0	n.s.
Body mass index (kg/m^2)	28.9 ± 3.3	27.9 ± 4.9	n.s.
EF (%)	60.0 ± 5.3	24.9 ± 5.9
LVEDD (mm)	48.2 ± 4.6	63.0 ± 11.1
LVESD (mm)	31.4 ± 5.1	54.0 ± 10.6
Pro-BNP (pg/mL)	148.4 (47.9; 178.0)	2338.5 (1475.6; 4597.5)
CRP (mg/L)	5.0 (1.3; 6.1)	2.6 (1.5; 4.9)	n.s.
Smoking (N)	1	3	n.s.
Diabetes mellitus (N)	2	4	n.s.
Hypertension (N)	13	19	n.s.
Ischemic heart disease (N)	3	9	n.s.

Statistical analysis: continuous variables are presented as mean ± SD or median (IQR) in case of variables that violated the normal distribution; categorical variables are presented as the number of affected patients in each group. In order to test the possible differences between the study groups, t-test or chi-square test was performed. Sign: significance; N: number; n.s.: nonsignificant; EF: ejection fraction; LVEDD: left ventricular end diastolic diameter; LVESD: left ventricular end systolic diameter; Pro-BNP: N-terminal probrain-type natriuretic peptide; CRP: C-reactive protein.