Oxidative Stress-Related Parthanatos of Circulating Mononuclear Leukocytes in Heart Failure

Table 3

Multivariate regression of the possible determinants of oxidative stress in chronic heart failure.

	Total peroxide (μmol/l); , ,			OSI; , ,
	B	SD of B	p^B	B	SD of B	p^B
Constant	−1611.2	713.8	0.087	−2.629	0.927	0.047
Log[pro-BNP (pg/mL)]	991.7	154.5	0.003	1.402	0.201	0.002
IHD	362.4	127.5	0.047	0.421	0.166	0.064
LVEDD	26.3	25.7	0.362	0.059	0.033	0.151
LVESD	−55.2	30.2	0.141	−0.101	0.039	0.062

Dependent variable was plasma total peroxide level (μmol/L), while independent variables were plasma pro-BNP, the occurrence of ischemic heart disease (IHD), LVEDD, and LVESD. r²: coefficient of determination of the model; p^A: significance level of the model; B: beta coefficient; p^B: significance level of the effect of each independent variable. OSI: oxidative stress index; pro-BNP: N-terminal probrain-type natriuretic peptide; IHD: ischemic heart disease; LVEDD: left ventricular end diastolic diameter; LVESD: left ventricular end systolic diameter.