Oxidative Medicine and Cellular Longevity / 2017 / Article / Tab 1

Review Article

Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits

Table 1

Important bioactive compounds in honey, propolis, and royal jelly.

Type of bee productBioactive compoundChemical structureBiological activityReferences

PropolisPhenolic compound: 2,2-dimethyl-8-prenylchromeneAntimicrobialViuda-Martos et al. [22]

PropolisPhenolic compound: 4-hydroxy-3,5-diprenyl cinnamic acid (artepillin C)Antimicrobial, anti-inflammatory, anticancerViuda-Martos et al. [22]

PropolisPhenolic compound: 3-prenyl cinnamic acid allyl esterAntimicrobialViuda-Martos et al. [22]

PropolisPhenolic compound: kaempferideAntitumor, anticancerViuda-Martos et al. [22], [23]

PropolisPhenolic compound: propolis benzofuranAntifungalViuda-Martos et al. [22], [23]

PropolisTerpenoid: isocupressic acid, a labdane diterpenoidAntifungalViuda-Martos et al. [22] (Khalil & Sulaiman [23])

PropolisTerpenoid:13C-symphyoreticulic acid, a clerodane diterpenoidAntitumorViuda-Martos et al. [22], [24]

PropolisTerpenoid: esters of long-chain fatty acids, (3-hydroxystearic acid () procrim a; 3-hydroxystearic acid (), procrim b and a pentacyclic triterpenoid (lupeol))Antioxidant, antimicrobial, antitumor(Salatino et al. [25]), Viuda-Martos et al. [22], (Huang et al. [13])

PropolisTerpenoid: farnesol, a sesquiterpenoidAntifungalViuda-Martos et al. [22], (Cotoras et al. [26])

Propolis, honeyFlavonoid: apigeninAntibacterial, anti-inflammatoryViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: acacetinAntiallergy, anticancerViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: quercetinAnticancer, antiallergy, antibacterial, anti-inflammatoryViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: galanginAnticancer, antioxidantViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: pinocembrinAntimicrobial, anticancerViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: chrysinAntibacterial, anti-inflammatory, anticancerViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Honey, propolisFlavonoid: fisetinAntibacterial, antiallergy, anticancerViuda-Martos et al. [22], (Abubakar et al. [27])

Honey, propolisFlavonoid: caffeic acid phenethyl esterAntitumor, anticancerViuda-Martos et al. [22], (Khalil & Sulaiman [23])

Propolis, royal jelly10-hydroxyl-2-decenoic acidAntibiotic, antitumorIzuta et al. [28]

HoneyFlavonoid: luteolinAntioxidant, anti-inflammatory, antitumorLin et al. [29], Mijanur et al. [30]

HoneyFlavonoid: pinobanksinAntioxidantAjao et al. [31]

HoneyFlavonoid: hesperetinAntioxidant, anti-inflammatoryKassim et al. [32], Mijanur et al. [30]

HoneyFlavonoid: naringeninNeuroprotective, antioxidantBadruzzaman Khan et al. [33], Mijanur et al. [30]

HoneyFlavonoid: genisteinAnticancerTahir et al. [34], Mijanur et al. [30]

HoneyPhenolic acid: p-coumaric acidAntigenotoxic, neuroprotectiveVauzour et al. [35], Mijanur et al. [30])

HoneyPhenolic acid: gallic acidAntianxiolyticMansouri et al. [36], Mijanur et al. [30]

HoneyPhenolic acid: ellagic acidAntioxidant, chemopreventive, antiproliferativeMijanur et al. [30]

HoneyPhenolic acid: ferulic acidAntioxidant, anti-inflammatory, neuroprotectiveMijanur et al. [30]

HoneyPhenolic acid: syringic acidAntioxidant, anticancerMijanur et al. [30], Tahir et al. [34]