(a) Serum
(b) Nontreated
(c) Treated with CHM
Figure 1: Effect of CHM administration on the pattern of serum enzyme activities at various times after 70% PH. Enzyme activities are expressed as mean ± SE for six independent determinations per experimental point for LDH, ALT, AST, GDH, and OCT, after 24 h after surgery. In panel (a), empty symbols represent 70%-PH rats, and solid symbols represent those PH animals in vivo treated with 1.8 mg/kg, b.w., of CHM, 6 h before euthanasia. Enzyme release in vitro from isolated livers from PH rats without (panel (b)) or with (panel (c)) in vivo treatment with CHM is also shown.