Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism

Figure 1

Effect of S-ISL on proliferation and cell cycle of cancer cells: The effects of S-ISL (3.125~50 μg/mL) on Tca8113, HepG2 and PC12 cells were observed for 24 h, 48 h, and 72 h using SRB assay (a) and the effects of S-ISL (6.25~50 μg/mL) on Tca8113 cell cycle were observed using FCM analysis (b). SRB results were expressed as the mean ± SD of three experiments with five replicates. S-ISL: synthetic isoliquiritigenin; SRB: sulforhodamine B; OD: optical density; IC₅₀: 50% growth inhibition concentration; FCM: flow cytometry. , versus the vehicle group.

(a)

(b)