Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide

Figure 5

DATS alleviates oxidative stress associated with H₂S in HSCs. (a) Analyses of intracellular ROS using a fluorescence microscope (100x magnification). (b, c) Analyses of intracellular ROS using flow cytometry with quantification. Significance: versus DMSO, versus DMSO, versus DMSO + H₂O₂, versus DMSO + H₂O₂, and ^& versus DATS + H₂O₂. (d, e) Analyses of intracellular LPO and GSH. Significance: versus DMSO, versus DMSO, versus DMSO + H₂O₂, versus DMSO + H₂O₂, versus DMSO + H₂O₂, and ^& versus DATS + H₂O₂.

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