Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats

Figure 2

Effects of AET and obesity on cardiac intramuscular fat content and cardiomyocyte diameter. Cardiomyocyte (CMO) diameter (a). Representative histological images stained with hematoxylin and eosin (b). Cardiac intramuscular fat contents (c) were evaluated by histological analysis in LZR (lean group control), LZR + TR (lean trained group), OZR (obese group control), and OZR + TR (obese trained group). (d) Representative histological images stained with oil red for intramuscular fat. Arrows indicate fat red staining. (e) Total heart weight corrected by tibia length in LZR (lean group control), LZR + TR (lean trained group), OZR (obese group control), and OZR + TR (obese trained group). ^† versus LZR + TR, versus OZR + TR versus LZR and LZR + TR, and ^# versus LZR and LZR + TR.

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