Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells

<div>Human mtDNA genome showing location of humanin and SHLPs (16sRNA) and MOTS-c (12S rRNA). Regions for subunits of other proteins are also indicated in the figure. rRNA: ribosomal RNA; ND1 to ND6 and ND4: subunits of NADH dehydrogenase complex (complex 1); COI to COIII: subunits of cytochrome c oxidase (complex 1V); ATP6 and ATP8: subunits of ATP synthase; Cyt b: cytochrome b of CoQ-cytochrome c reductase (complex III).</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells 