Effect of Emodin on Preventing Postoperative Intra-Abdominal Adhesion Formation

Figure 1

Emodin treatment prevents postoperative intra-abdominal adhesion formation in rats on the seventh day after the operation (). (a) The sham operation group (sham) rarely had intra-abdominal adhesions. Control group (control) animals developed a large number of extensive and thick adhesions that were difficult to separate. The sodium hyaluronate group (HA) had a few adhesion formations. The low-dose emodin group, middle-dose emodin group, and high-dose emodin group developed fewer adhesions than the control group. Black arrows indicate adhesions. (b) The Lauder scores of the different groups (total compared with the control group, and , abnormally distributed, Kruskal-Wallis test). (c) The total Hoffmann scores of the different groups (total compared with the control group, and , abnormally distributed, Kruskal-Wallis test). (d) The nonadhesion rates in the different groups (total compared with the control group, , Fisher’s exact test).

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