Apple Flavonoids Suppress Carcinogen-Induced DNA Damage in Normal Human Bronchial Epithelial Cells

Figure 6

(a) Effects of AF4 on various DDR signaling proteins exposed to NNK-Ae or MTX as assessed by western blotting. (b), (c), (d), (e), (f), (g), and (h) The relative amount of each protein expression levels (DNA-PK, p-ATR, p-ATM, p-Chk2, p-Chk1, p-P53, and γ-H2AX) with respect to beta-actin loading control, quantified from at least 3 independent experiments. indicated statistical difference at with mean ± SD. ns: nonsignificant.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)