YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission

Figure 1

YQFM protects against cerebral I/R injury and mitochondrial apoptosis. Rats were subjected to 1.5 h of ischemia, followed by 24 h of reperfusion. YQFM (0.957 g/kg) was administered intraperitoneally after ischemia. (a) Representative TTC-stained brain sections. (b) Quantitative analysis of infarct volume. (c) H&E stained sections of rat brains. (d) Quantitatification of neurologic deficit scores (). Expression of Bcl-2 (e), Bax (f), and cleaved caspase-9 (g) in ischemic brain tissue. Results were expressed as mean ± SD from three independent experiments. versus Sham, versus I/R, versus I/R.

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