Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Figure 3

Effects of apoCIII overexpression and high-fat diet consumption on the expression of lipogenesis-related genes. mRNA expression levels for (a) CD36, (b) ChREBP, (c) SREBP1c, (d) ACC, (e) FAS, and (f) SCD1 in the livers of NTg and apoCIII mice fed either a low-fat (LF) or high-fat (HF) diets were analyzed and normalized to β-actin ( = 6–8). Data are expressed as the mean ± SEM. versus HF group; versus apoCIII mice (; two-way ANOVA). values with nonmatching superscript letters are significantly different (; ANOVA followed by Bonferroni correction).

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