Research Article

Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Table 4

Food intake; body, liver, and adipose tissue masses; and fasting plasma concentrations of lipids and leptin in NTg and CIII mice fed a high-fat diet (HFD) and treated or not with fenofibrate (HFD/F).

HFDHFD/F
NTgCIIINTgCIII

Food intake (kcal/animal/day)
(5)(5)(4)(4)
Body weight (g)
(9)(6)(6)(6)
Liver (% body weight)
(7)(8)(6)(6)
Perigonadal WAT (%)
(6)(7)(6)(6)
Plasma triglycerides (mg/dL)
(7)(7)(7)(7)
Plasma cholesterol (mg/dL)
(6)(6)(6)(6)
Nonesterified fatty acids (mEq/L)
(7)(8)(6)(6)
Plasma leptin (pg/mL)
(6)(5)(6)(6)

Mean ± SEM (). versus HFD/F groups; versus apoCIII mice (; two-way ANOVA).