Ghrelin Protects Human Lens Epithelial Cells against Oxidative Stress-Induced Damage

Figure 4

Morphological observations confirmed the reduction in opacity when the lenses were incubated in ghrelin. Whole lenses were pretreated with ghrelin at concentrations of 10⁻⁹–10⁻⁶ M for 24 h and then cultured for 6 h with 100 μM H₂O₂. The control group received no treatment, and the H₂O₂ group was treated only with 100 μM H₂O. Photographs were taken against a background of black gridlines. The higher the concentrations of ghrelin, the less opacity was observed in the lenses.