Apigenin Alleviates Endotoxin-Induced Myocardial Toxicity by Modulating Inflammation, Oxidative Stress, and Autophagy

Figure 1

Apigenin attenuates LPS-induced cardiac injuries. Cardiac injuries were measured by plasma LDH and CK. LDH and CK plasma levels were increased in LPS-treated mice. Increase of LPS-induced cardiac injury was significantly attenuated by apigenin treatment. Values represented as means ± SD; and . Control was a vehicle-treated group where Apig was apigenin-treated group. LPS and Apig + LPS were administered with LPS along with posttreatment of vehicle or apigenin. Same nomenclature was used in all other figures.