Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches

Figure 3

Bioinformatics correlation between oxidative stress gene expressions and poor prognosis in 6 different tumor types. Heat map in which we report in red or in green if the high or low expression of genes was negatively correlated with survival, respectively. Moreover, we evidenced in yellow when the correlation is statistically significant (with value <0.05). In the first column, we evidenced in magenta, the genes similar modulated among cancers and in blue those oxidative stress family extracted from STRING analysis. Notably TXNRD1 showed a central role in both analyses.