Protective Effect of Icariin on the Development of Preimplantation Mouse Embryos against Hydrogen Peroxide-Induced Oxidative Injury

<div>ICA increase H<sub>2</sub>O<sub>2</sub>-induced intracellular mitochondrial membrane potential (Δ<i>Ψ</i>m) in KM mouse zygotes. Representative photomicrographs of inner mitochondrial membrane potential (Δ<i>Ψ</i>m) in zygotes treated with H<sub>2</sub>O<sub>2</sub> or H<sub>2</sub>O<sub>2</sub> plus ICA. Zygotes were stained with JC-1. Red fluorescence represented J-aggregates (high-polarized mitochondria), and green fluorescence represented monomer form of JC-1 (low-polarized mitochondria). Bar = 100 <i>μ</i>m.</div>

Oxidative Medicine and Cellular Longevity

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Figure 4

Figure 4: Protective Effect of Icariin on the Development of Preimplantation Mouse Embryos against Hydrogen Peroxide-Induced Oxidative Injury 