Protective Effect of Icariin on the Development of Preimplantation Mouse Embryos against Hydrogen Peroxide-Induced Oxidative Injury

Table 1

The effects of transient treatment of different concentrations of H₂O₂ on the development of KM mouse 1-cell embryos in vitro.

Group	1-cell embryos	2-cell embryos (%)	4-cell embryos (%)	Blastocysts (%)
KSOM	205	196 (95.61)	190 (92.68)	179 (87.32)
20 μM H2O2	195	177 (90.77)	170 (87.18)	158 (81.03)
40 μM H2O2	180	127 (70.56)	109 (60.56)	101 (56.11)
60 μM H2O2	208	109 (52.40)	88 (42.31)	68 (32.69)
80 μM H2O2	80	0 (0.00)	0 (0.00)	0 (0.00)

Note: The percentage is based on the numbers of 1-cell embryos. Differences between the groups were calculated using the χ²-test. versus the KSOM group.