|
Trial number status | Conditions and dosage | Objectives | Primary outcome | Number of subjects (age/sex) |
|
NCT02613715 (completed) | Overweight and obesity (250 ml of blackberry juice) | To evaluate the bioavailability of blackberry juice anthocyanins in normal weight and overweight/obese adults | Plasma concentrations of anthocyanins and anthocyanin metabolites | 18 (18–40/M-F) |
NCT01180712 (recruiting) | Type 2 diabetes (1.4 g of concentrated blackberry extract mirtoselect provided by Indena S.p.A.) | To determine the effects of anthocyanin supplementation in the form of a concentrated blackberry extract on insulin resistance and inflammation particularly in the adipose tissue | Oral glucose tolerance test | 60 (40–70/M) |
NCT01883401 (completed) | Dyslipidemia; obesity (25–50 g freeze-dried strawberries/day) | To determine the effects of low and high doses of freeze-dried strawberries in cardiovascular risk factors in subjects with abdominal adiposity and dyslipidemia | Change in lipids and lipoproteins | 60 (19–72/M-F) |
NCT01005420 (completed) | Insulin sensitivity (45 g of blueberry powder) | To evaluate the effect of blueberry powder on insulin sensitivity in obese, nondiabetic, and insulin-resistant subjects. | Insulin sensitivity | 37 (>20/M-F) |
NCT02689765 (completed) | Insulin resistance; glucose and lipid metabolism disorders; type 2 diabetes (80 g of a mixture of fresh blueberries and blackcurrants) | To characterize the potential effects of anthocyanins, purified from bilberries and blackcurrants, on metabolic zabnormalities commonly associated with type 2 prediabetes | Change in fasting glucose and HbA1C | 160 (40–75/M-F) |
NCT01705093 (unknown) | Childhood obesity; cardiovascular disease (50 g of flavonoid-rich freeze-dried strawberry powder) | To verify if strawberry intake can lead to improvements in select measures of cardiovascular function in overweight and obese adolescent males | Vascular function measured by peripheral arterial tonometry | 25 (14–18/M) |
NCT02035592 (active, but not recruiting) | Insulin resistance; metabolic syndrome X (13–26 g of freeze-dried blueberry powder per day) | To determine the dose-dependent impact of blueberry powder intake on insulin sensitivity and resistance, cardiovascular disease risk factors, and lung and cognitive function in overweight and obese participants with metabolic syndrome | Insulin resistance | 144 (50–74/M-F) |
NCT02291250 (recruiting) | Type 2 diabetes (200 g of blackcurrants, which contain anthocyanins, or 200 g greencurrants, which naturally contain no anthocyanins) | To investigate the acute effect blackcurrants on glucose metabolism in overweight/obese volunteers | Plasma glucose area under the curve | 16 (21–70/M-F) |
NCT02800967 (active, but not recruiting) | Hypertension; overweight (pure Aronia juice with appx. polyphenol content of 1000 mg gallic acid equivalents/100 ml) | To investigate the effects of Aronia juice polyphenols on platelet function and other CVD risk factors in subjects with moderate CVD risk | Changes in the percentage of P-selectin and glycoprotein IIbIIIa (GPIIbIIIa) positive platelets, percentage of platelet-monocyte, and platelet-neutrophil aggregates | 84 (30–50/M-F) |
NCT01564498 (recruiting) | Hypertension; hypercholesterolemia; type II diabetes; obesity; inflammation (300–500 g of cooked white/purple potatoes per day, or 300–500 g of raw orange/purple carrots per day) | To verify if purple vegetables, rich in polyphenolic compounds including anthocyanins, can have higher antioxidant and other biological activities than more lightly coloured versions of these foods | Blood cholesterol | 60 (18–65/M-F) |
|